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Combating Opioid Overdose Through Community-Level Intervention (COOCLI)



Application Deadline: Nov 2, 2020

Sponsoring Organization

Centers for Disease Control and Prevention (CDC)


Provides funding to conduct and evaluate research designed to help communities address opioid and stimulant overdose in regions of the U.S. with the highest rates of fatal and non-fatal overdose.

Grants are awarded following a two-tier system.

  • Tier 1 awards support the development of small innovative projects utilizing a novel program, strategy, or approach that has not been evaluated, or projects that adapt an existing evidence-based strategy for use in new setting or with new populations
  • Tier 2 awards focus on implementation and evaluation of medium-sized projects that have some evidence base but would benefit from full implementation and evaluation

Required grant activities include:

  • Implementing new community-based programs or enhancing existing programs using evidence-based or promising practices to reduce opioid or stimulant-involved overdose
  • Evaluating program activities and approaches in order to assess their effectiveness
  • Promoting collaboration between public safety and public health agencies to help expand and coordinate community-level prevention and intervention efforts

Amount of Funding

  • Tier 1: Up to $150,000
  • Tier 2: $150,001 to $300,000

Project period: 1 year
Estimated total program funding: $2,000,000

Who Can Apply

Applications may be submitted by:

  • High Intensity Drug Trafficking Areas (HIDTA) programs
  • Public/State-controlled and private institutions of higher education
  • Nonprofit organizations with or without 501(c)(3) status
  • State governments
  • County, city, township, or special district governments
  • Federally recognized Native American tribal governments
  • Native American tribal governments and tribal organizations other than federally recognized
  • U.S. territories or possessions
  • Independent school districts
  • Public housing authorities and Indian housing authorities
  • Faith-based or community-based organizations

Applicant organizations:

  • Must partner with a regional High Intensity Drug Trafficking Areas (HIDTA) program, and applications must include a letter of support/commitment from the participating HIDTA signed by the sponsoring HIDTA Director
  • Must have expert knowledge and extensive experience in conducting research and analysis
  • Must have expert knowledge and experience developing or enhancing new or ongoing programs that aim to reduce opioid or other drug overdose through strategic, evidence-based approaches

Priority is given to proposed projects that implement and/or evaluate evidence-based or promising programs.

Geographic Coverage


What This Program Funds

Buildings and Facilities • Capacity Building • Equipment • New Program • Operating Costs and Staffing

Application Process

Application instructions, requirements, and other information about the application process are available in the program guidance.


For program questions or general assistance:
Sherae Lonick

Rural Awards

Examples of past 2018 and 2017 awards communities have received are described on the program website.

Rural communities who have received funding include:

  • The North Carolina Harm Reduction Coalition received a 2018 COOCLI award to fund the Strengthening Overdose Prevention Efforts in Rural Areas Through Participant-Driven Innovation project.
  • The Kingman Police Department received 2017 COOCLI funding to implement the Multi-Sector Incarceration Alternative and Harm Reduction Approaches to Combat the Opioid Epidemic in Rural Arizona program.

Topics This Program Addresses

Community Planning and Coalition Building • Harm Reduction • Justice System • Opioids • Overdose Prevention