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Overdose Data to Action in States


Additional Links

Notice of Funding Opportunity (


Letter of Intent (Optional): Mar 27, 2023
Application Deadline: May 8, 2023


Centers for Disease Control and Prevention (CDC)


Awards funding to strengthen state health departments' ability to track and prevent nonfatal and fatal overdoses and identify emerging drug threats. Supports surveillance strategies and evidence-based prevention activities focused on opioids, stimulants, and polysubstance use to reduce morbidity and mortality due to overdose. Seeks to reduce health disparities and increase access to care and services for populations most at risk of overdose, including rural communities and tribal populations.

Grant recipients must fulfill both the surveillance and prevention components of the funding program.

The Surveillance Component is composed of 3 required strategies focused on:

  1. Surveillance Infrastructure to improve and enhance overall capacity to conduct surveillance
  2. Morbidity to collect and disseminate timely data from emergency departments and hospital admissions for suspected overdoses
  3. Mortality to collect and disseminate timely data on unintentional and undetermined intent drug overdose deaths

An optional, competitive application process is available for the following surveillance strategies:

  1. Biosurveillance
  2. Data linkage

The Prevention Component is comprised of 4 required strategies focused on:

  1. Clinician/Health System Engagement and Health IT and Prescription Drug Monitoring Program (PDMP) enhancement to provide clinician education on evidenced-based practices for pain management, screening, diagnosis, and linkage to care for opioid use disorder (OUD) and stimulant use disorder (StUD); to build clinical capacity to screen, diagnose, and support longitudinal care for OUD and StUD and support recovery; to support and expand integration of PDMP date with health IT systems and data sharing between states; to promote universal PDMP use among clinicians; proactively manage PDMP, and more
  2. Public Safety Partnerships and Interventions to improve data sharing, availability, and use by developing and maintaining public health and health safety partnerships; provide overdose education on preventing and responding to overdose; implement evidenced-informed and evidence-based overdose prevention response strategies
  3. Harm Reduction includes the use of navigators to ensure access to treatment options, overdose prevention and reversal tools, and drug checking equipment; creating and disseminating education and communication materials; and partnerships with syringe services and other harm reduction organizations
  4. Community-Based Linkage to Care includes activities to link individuals to care, retain them in care and maintain recovery

Amount of Funding

Award ceiling: $7,000,000 per year
Award floor: $1,400,000 per year
Project period: 5 years
Estimated number of awards: 51
Estimated total program funding: $995,000,000

Who Can Apply

State health departments or their bona fide agents are eligible to apply.

Geographic Coverage


What This Program Funds

Capacity Building • Operating Costs and Staffing

Application Process

Application instructions, requirements, and other information about the online application process are available in the funding announcement.

To apply for the optional, competitive surveillance strategies 4 and 5, applicants must indicate which strategy or strategies they are applying for in the project abstract.

Letter of intent (LOI) requested but not required.

Applicant webinar recording


For programmatic or technical questions:
Jamie Mells

For grants management or budget questions:
Keisha Thompson

Topics This Program Addresses

Harm Reduction • Naloxone • Opioids • Overdose Prevention • Pain Management and Opioid Prescribing • Prevention • Recovery • Substance Use Disorder • Treatment