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State Opioid Response Grants (SOR)


Additional Links

Notice of Funding Opportunity (


Application Deadline: Jul 18, 2022


Substance Abuse and Mental Health Services Administration (SAMHSA)


Aims to address the opioid crisis by providing states with formula grants to increase access to Food and Drug Administration (FDA)-approved medications for the treatment of opioid use disorder (MOUD). Supports prevention, harm reduction, treatment, and recovery support services for opioid use disorder (OUD) and other concurrent substance use disorders. Also supports the continuum of care for stimulant misuse and use disorders, including cocaine and methamphetamine. Supports the development of the skills and abilities reduce unmet treatment needs and to address opioid overdose deaths.

Required program activities include:

  • Developing a needs assessment from statewide epidemiological data or, if a needs assessment process is already established, collaborate with the local, state, or tribal epidemiological outcomes workgroup to improve and augment the existing process and its discoveries, to perform the following assessments:
    • Determining the scope of OUD, substance use disorder (SUD), and overdose mortality in recent years
    • Identifying strengths, unmet service needs, gaps is the care for racial, ethnic, geographic, and other demographic groups
    • Identifying locations where frequent opioid and stimulant misuse, SUD, overdose, and related activities occur
    • Determining the amount and location of opioid treatment providers in the state, including opioid treatment programs (OTPs)
    • Identifying established practices and funding sources that address opioid and stimulant use prevention, harm reduction, treatment, and recovery efforts and activities in the state
    • A naloxone distribution and saturation plan that focuses on areas with high overdose mortality rates
  • Forming comprehensive, statewide strategies to fill identified gaps in opioid and stimulant related services
  • Implement evidence-based practices and models to support treatment and recovery support services focused on positive and long term recovery outcomes from OUD and stimulant use disorder
  • Implement recovery support services and provide harm reduction services
  • Provide treatment transition and coverage for individuals reentering communities from criminal justice settings or other rehabilitative settings
  • Utilize the related, SAMHSA-funded technical assistance and training resources

Amount of Funding

Funds are distributed by formula based on the state's proportion of drug overdose deaths, based on data from the Centers for Disease Control and Prevention, and the state's proportion of people who meet diagnostic criteria for dependence or abuse of heroin or pain relievers who report not having received any treatment, based on data from the National Survey on Drug Use and Health (NSDUH). Annual award amounts can be found in Appendix K of the funding announcement.

Project period: Up to 2 years
Estimated number of awards: 59
Estimated total program funding: $1,439,500,000

Who Can Apply

Single state agencies (SSAs) are eligible to apply.

Geographic Coverage


What This Program Funds

Capacity Building • Equipment • New Program • Operating Costs and Staffing

Application Process

Application instructions, requirements, and other information can be found in the funding announcement.


For programmatic questions:
C. Danielle Johnson Byrd

For grants management or budget questions:

For grants management or budget questions:
Sara Fleming

Topics This Program Addresses

Community Planning and Coalition Building • Health and Wellness • Justice System • Medication-Assisted Treatment (MAT) • Naloxone • Opioids • Pain Management and Opioid Prescribing • Prevention • Recovery • Substance Use Disorder • Teleservices and Technology • Treatment