Clinical Practice Guideline for the Management of Substance Use Disorders


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Sponsoring Organization

Veterans Health Administration (VHA)


Offers evidence-based information, recommendations, guides, and tools to Department of Veterans Affairs (VA) and Department of Defense (DoD) healthcare providers and patients to assist in the decision making process to improve the treatment and outcomes for patients with substance use disorder (SUD), including opioid use disorder (OUD) and methamphetamine use, and co-occurring mental health conditions. Describes best practices to help patients avoid preventable complications, reduce substance use, and improve their overall health and wellness.

Geographic Coverage



Harm Reduction • Health and Wellness • Healthcare Workforce • Medication-Assisted Treatment (MAT) • Mental Health • Methamphetamine • Naloxone • Opioids • Prevention • Recovery • Substance Use Disorder • Suicide and Suicide Prevention • Treatment • Veterans