Consists of a network of 10 regional centers, a central coordinating office, a National Hispanic and Latino ATTC, and a National American Indian and Alaska Native ATTC working in addiction treatment and recovery services. Promotes awareness and new and evidence-based practices and services for the treatment of opioid use disorder (OUD) and substance use disorder (SUD). Facilitates the adoption of new technology by addiction treatment and recovery service providers. Offers education, training, resources, and information for the behavioral healthcare workforce in rural areas.

Delivers information, resources, technical assistance, and training to K-12 schools and institutions of higher learning to assess school climate, implement evidence-based programs to improve learning conditions, and measure outcomes in 3 core areas: providing a well-rounded education, improving the safety and health of students, and improving the effective use of technology. Offers multiple products, policy guides, toolkits, research, media, online events and training related to issues of substance and opioid abuse for students, families, schools, and communities.

Serves as a Rural Opioid Technical Assistance Regional Center (ROTA-R) providing training and technical assistance to address opioids, stimulants, and other substances impacting rural communities in New Jersey, New York, Puerto Rico, and the U.S. Virgin Islands.

Serves as a Rural Opioid Technical Assistance Regional Center (ROTA-R) in New England. Provides support, technical assistance, and naloxone training to address opioid use disorder (OUD), stimulant use, and opioid overdose throughout rural areas in Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont.

Consists of a network of 10 regional resource centers, a central coordinating office, a National Hispanic and Latino PTTC, and a National American Indian and Alaska Native PTTC that work to support effective substance use prevention interventions. Develops and disseminates education, training, resources, and information to raise awareness and promote the implementation of evidence-based prevention practices. Facilitates the adoption of new technology by individuals and organizations working in the field of substance use prevention. PTTC focus areas include community coalitions and collaborators; health equity and inclusion; data-informed decisions; implementation science; cannabis prevention; and workforce development.

Offers support services, technical assistance, information, and training to K-12 schools and institutions of higher education to help strengthen their emergency preparedness. Includes information and resources on the development of emergency operation plans, including how to prepare for opioid-related emergencies and support students dealing with substance use issues in rural and urban areas.

Serves as a Rural Opioid Technical Assistance Regional Center (ROTA-R) in the Southeast region of the U.S. Develops training and provides technical to address opioid and stimulant use in rural communities. Supports rural communities in Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee.